GLOBAL ADDITIVES CATALOG

E-Number & Chemical Additive Dictionary

Search over 1,000 food additives, synthetic petroleum dyes, chemical preservatives, and INS numbers evaluated against EFSA and WHO toxicity benchmarks.

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INS 102 / E102

Tartrazine

Synthetic Food Color (Azo Dye)
⚠️ High Hazard

Yellow synthetic azo dye derived from petroleum. Strongly linked to hyperactivity, ADHD, and asthma in children under 8.

KEY HEALTH RISKS:
Pediatric Hyperactivity / ADHD Asthma & Hives Triggers Potential Allergic Sensitivity
INS 110 / E110

Sunset Yellow FCF

Synthetic Food Color (Azo Dye)
⚠️ High Hazard

Orange petroleum-based azo dye commonly used in candies, sodas, and processed snacks.

KEY HEALTH RISKS:
Pediatric Attention Deficits Allergic Reactions Eczema Flare-ups
INS 122 / E122

Carmoisine (Azorubine)

Synthetic Food Color (Azo Dye)
⚠️ High Hazard

Red synthetic azo dye used in jellies, marzipan, and sweets. Causes hypersensitivity and child hyperactivity.

KEY HEALTH RISKS:
Pediatric Hyperactivity Skin Rash / Hives Allergic Rhinitis
INS 124 / E124

Ponceau 4R

Synthetic Food Color (Azo Dye)
⚠️ High Hazard

Strawberry red synthetic azo dye. Known to trigger severe intolerance reactions in aspirin-sensitive individuals.

KEY HEALTH RISKS:
Pediatric Attention Deficits Asthma Trigger Intolerance Reactions
INS 127 / E127

Erythrosine

Synthetic Organoiodine Color
⚠️ High Hazard

Cherry red dye containing iodine. Shown in animal studies to induce thyroid tumors.

KEY HEALTH RISKS:
Thyroid Tumor Risk Iodine Sensitivity Pediatric Hyperactivity
INS 129 / E129

Allura Red AC

Synthetic Food Color (Azo Dye)
⚠️ High Hazard

Dark red synthetic azo dye. Implicated in behavioral issues in young children and gut lining inflammation.

KEY HEALTH RISKS:
Pediatric Hyperactivity Gut Microbiome Imbalance Hypersensitivity
INS 133 / E133

Brilliant Blue FCF

Synthetic Triarylmethane Color
⚠️ Moderate Hazard

Blue synthetic dye derived from petroleum. Can induce bronchoconstriction in asthma sufferers.

KEY HEALTH RISKS:
Bronchoconstriction in Asthmatics Cellular Toxicity Allergic Sensitivity
INS 150d / E150d

Ammonia Caramel (Caramel IV)

Synthetic Colorant
🚨 Carcinogenic Hazard

Dark brown color produced by heating sugars with ammonium and sulfite compounds. Generates 4-MEI carcinogen byproduct.

KEY HEALTH RISKS:
4-MEI Carcinogenic Byproduct Lung & Liver Tumor Link Immune System Stress
INS 171 / E171

Titanium Dioxide

White Mineral Pigment
🚨 Banned in EU / Genotoxic

Inorganic white pigment particle. Banned across the EU by EFSA due to genotoxicity and DNA strand damage.

KEY HEALTH RISKS:
Genotoxicity & DNA Damage Intestinal Absorption Hazard Cellular Inflammation
INS 202 / E202

Potassium Sorbate

Antimicrobial Preservative
🟡 Low Hazard

Synthetically produced sorbic acid salt used to inhibit molds and yeasts in cheese, wine, and baked goods.

KEY HEALTH RISKS:
Mild Skin & Eye Irritation Generally Well Tolerated
INS 211 / E211

Sodium Benzoate

Preservative
⚠️ High Hazard

Antimicrobial preservative. Reacts with Vitamin C (Ascorbic Acid) in beverages to form carcinogenic Benzene.

KEY HEALTH RISKS:
Forms Carcinogenic Benzene with Vit C Cell Damage & DNA Risk Pediatric Hyperactivity Trigger
INS 220 / E220

Sulfur Dioxide

Sulfite Preservative & Bleaching Agent
⚠️ High Hazard

Sulfite gas used to prevent browning in dried fruits and wine. Destroys Vitamin B1 (Thiamine) and triggers severe asthma attacks.

KEY HEALTH RISKS:
Destroys Thiamine (Vit B1) Severe Asthma Attacks Allergic Hypersensitivity
INS 250 / E250

Sodium Nitrite

Cured Meat Preservative & Fixative
🚨 Carcinogenic Hazard

Preservative used in cured meats (bacon, sausages, hot dogs). Reacts with stomach amines to form carcinogenic Nitrosamines.

KEY HEALTH RISKS:
Colorectal & Stomach Cancer Risk Nitrosamine Toxicity Infant Methemoglobinemia Risk
INS 282 / E282

Calcium Propionate

Bread Mold Inhibitor
⚠️ Moderate Hazard

Preservative used in commercial packaged breads to prevent mold growth. Linked to restlessness and sleep disturbance in children.

KEY HEALTH RISKS:
Pediatric Sleep Disturbances Irritability & Restlessness Migraine Triggers
INS 300 / E300

Ascorbic Acid (Vitamin C)

Natural Antioxidant
🟢 Safe / Nutritious

Essential Vitamin C nutrient used as an antioxidant to prevent browning and dough degradation.

KEY HEALTH RISKS:
Essential Vitamin C Nutrient Antioxidant Cell Protection Safe
INS 306 / E306

Tocopherols (Vitamin E)

Natural Antioxidant
🟢 Safe / Nutritious

Natural Vitamin E extract used to prevent fat and oil oxidation naturally.

KEY HEALTH RISKS:
Essential Vitamin E Nutrient Protects Cell Membranes Safe
INS 319 / E319

TBHQ (Tertiary Butylhydroquinone)

Synthetic Antioxidant Preservative
⚠️ High Hazard

Synthetic petroleum-derived antioxidant used in fried foods, instant noodles, and fats. High doses linked to stomach tumors and vision disturbances.

KEY HEALTH RISKS:
Stomach Tumor Link in Animal Studies Liver Enlargement Neurotoxic Effects
INS 320 / E320 & INS 321 / E321

BHA & BHT (Butylated Hydroxyanisole / Hydroxytoluene)

Synthetic Preservative
🚨 Carcinogenic Hazard

Synthetic antioxidant preservative used to prevent fat rancidity. Classified by IARC as a potential human carcinogen and endocrine disruptor.

KEY HEALTH RISKS:
Carcinogenic Tumor Risk Endocrine & Hormone Disruption Thyroid Enlargement
INS 322 / E322

Lecithin (Soy / Sunflower)

Natural Emulsifier
🟢 Safe / Clean

Natural phospholipid extracted from soybeans or sunflower seeds. Essential for brain cell membrane structure.

KEY HEALTH RISKS:
Essential Choline Nutrient Source Brain Health Support Safe
INS 330 / E330

Citric Acid

Acidity Regulator
🟢 Safe / Natural

Natural organic acid found in citrus fruits. Used to adjust acidity and preserve freshness.

KEY HEALTH RISKS:
Natural Acidulant Enhances Mineral Absorption Safe
INS 338 / E338

Phosphoric Acid

Acidulant & Preservative
⚠️ High Hazard

Inorganic acidulant used primarily in cola soft drinks. Excess intake leaches calcium from bones and erodes tooth enamel.

KEY HEALTH RISKS:
Bone Density Loss & Osteoporosis Risk Dental Enamel Erosion Kidney Stone Risk
INS 407 / E407

Carrageenan

Seaweed Thickener / Stabilizer
⚠️ High Hazard

Red seaweed extract used as a thickener in plant milks and ice creams. Degraded carrageenan causes intestinal ulceration and gut inflammation.

KEY HEALTH RISKS:
Gut Inflammatory Trigger Intestinal Mucus Erosion Ulcerative Colitis Link
INS 412 / E412

Guar Gum

Natural Seed Thickener
🟢 Safe / Clean

Natural dietary fiber derived from guar beans. Acts as a thickener and prebiotic dietary fiber.

KEY HEALTH RISKS:
Natural Soluble Fiber Source Supports Gut Microbiome Safe
INS 415 / E415

Xanthan Gum

Natural Fermentation Thickener
🟢 Safe / Clean

Polysaccharide produced by simple sugar fermentation. Natural stabilizer for gluten-free baking and sauces.

KEY HEALTH RISKS:
Natural Fermentation Hydrocolloid Prebiotic Fiber Source Safe
INS 420 / E420

Sorbitol

Sugar Alcohol / Humectant
⚠️ Moderate Hazard

Polyol sweetener derived from glucose. Slow-digesting polyol that draws water into the colon, causing laxative distress in high amounts.

KEY HEALTH RISKS:
Osmotic Laxative Distress Abdominal Bloating & Gas IBS Symptoms
INS 471 / E471

Mono- & Diglycerides of Fatty Acids

Food Emulsifier
⚠️ Moderate Hazard

Synthetic fat emulsifier used in packaged cakes, breads, and peanut butter. May contain hidden trans-fat residues.

KEY HEALTH RISKS:
Hidden Trans Fat Residues Gut Lining Barrier Stress
INS 476 / E476

Polyglycerol Polyricinoleate (PGPR)

Synthetic Chocolate Emulsifier
⚠️ Moderate Hazard

Cheap synthetic emulsifier derived from castor oil. Used in commercial chocolates as a cocoa butter substitute. Alters gut mucus barrier in kids.

KEY HEALTH RISKS:
Gut Mucus Barrier Erosion Liver & Kidney Stress in High Doses
INS 500 / E500

Sodium Bicarbonate (Baking Soda)

Leavening Agent & Acid Regulator
🟢 Safe / Natural

Natural alkaline salt used as a raising agent in baking and as an antacid.

KEY HEALTH RISKS:
Safe Raising Agent Neutralizes Excess Stomach Acid
INS 551 / E551

Silicon Dioxide

Anti-Caking Agent
⚠️ Moderate Hazard

Amorphous silica powder added to powdered coffee, salt, and spices to prevent clumping. Nano-sized silica particles under investigation for intestinal inflammation.

KEY HEALTH RISKS:
Nanoparticle Intestinal Exposure Potential Cellular Stress
INS 621 / E621

MSG (Monosodium Glutamate)

Flavor Enhancer (Excitotoxin)
⚠️ Moderate Hazard

Flavor enhancer that hyper-stimulates brain glutamate receptors. Acts as an excitotoxin that can overstimulate nerve cells.

KEY HEALTH RISKS:
Excitotoxicity in Developing Neurons Chinese Restaurant Syndrome (Headaches) Overeating Stimulation
INS 627 / E627 & INS 635 / E635

Disodium Guanylate & I+G (Ribonucleotides)

Synergistic Flavor Enhancer
⚠️ Moderate Hazard

High-potency flavor enhancers used alongside MSG in chips and seasoning packets. Metabolized into purines which convert to uric acid.

KEY HEALTH RISKS:
Metabolizes to Uric Acid (Gout Trigger) Purpuric Skin Rashes in Sensitive Kids
INS 950 / E950

Acesulfame Potassium (Ace-K)

Artificial Sweetener
⚠️ High Hazard

Calorie-free artificial sweetener 200x sweeter than sugar. Contains methylene chloride solvent residues.

KEY HEALTH RISKS:
Contains Methylene Chloride Solvent Residue Gut Microbiota Disruption Insulin Resistance Link
INS 951 / E951

Aspartame

Artificial Sweetener
🚨 WHO 2B Carcinogen

Non-nutritive sweetener 200x sweeter than sugar. Officially classified by WHO/IARC as "possibly carcinogenic to humans" (Group 2B).

KEY HEALTH RISKS:
WHO Group 2B Carcinogen Listing Gut Microbiota Damage Unsafe for Phenylketonuria (PKU) Patients
INS 955 / E955

Sucralose

Chlorinated Artificial Sweetener
⚠️ High Hazard

Chlorinated artificial sweetener 600x sweeter than sugar. When heated during baking, forms toxic chloropropanols and dioxin-like compounds.

KEY HEALTH RISKS:
Generates Chloropropanol Toxins When Baked Alters Gut Microbiota Diversity Blunts Insulin Sensitivity
INS 960 / E960

Steviol Glycosides (Stevia)

Natural Non-Caloric Sweetener
🟢 Safe / Natural

Natural plant-derived sweetener extracted from Stevia rebaudiana leaves. Does not spike blood sugar or insulin.

KEY HEALTH RISKS:
Zero Blood Sugar Impact Natural Plant Extraction Safe
N/A

Palm Oil / Hydrogenated Fats

Refined Industrial Fat
⚠️ High Hazard

High in saturated palmitic acid. When refined at high industrial temperatures (> 200°C), generates toxic Glycidyl Fatty Acid Esters (GE) and 3-MCPD carcinogens.

KEY HEALTH RISKS:
3-MCPD & GE Thermal Carcinogen Contaminants Raises LDL Bad Cholesterol Coronary Artery Disease Risk
N/A

High Fructose Corn Syrup (HFCS)

Refined Caloric Sweetener
⚠️ High Hazard

Industrial corn sweetener that bypasses insulin-regulated hepatic metabolism, driving rapid visceral fat storage and fatty liver disease.

KEY HEALTH RISKS:
Non-Alcoholic Fatty Liver Disease (NAFLD) Pediatric Obesity & Type 2 Diabetes Rapid Visceral Fat Deposition
INS 100 / E100

Turmeric / Curcumin

Natural Superfood Component
🌟 Superfood

Natural botanical extract rich in anti-inflammatory curcuminoids.

KEY HEALTH RISKS:
Anti-inflammatory Antioxidant Cell Protection Immune Support
N/A

Whole Grain Oats / Beta-Glucan

Whole Grain Superfood
🌟 Superfood

Rich in soluble beta-glucan fiber which actively binds cholesterol and stabilizes blood glucose.

KEY HEALTH RISKS:
Lowers LDL Cholesterol Sustained Energy Prebiotic Gut Health